Get an Estradiol (generic Vagifem) prescription online
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Estradiol is an estrogen medication that providers often prescribe as part of women’s hormone therapy (HT). It replaces estrogen loss common during perimenopause and menopause, relieving symptoms like hot flashes, night sweats and vaginal dryness while supporting bone health. Estradiol comes in different forms, including patches and vaginal tablets.
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How Dr. B treats HRT
Tell us about your condition with a $15 online consultation.
A medical provider will review your information and prescribe treatment, if appropriate.
Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.
About Estradiol (generic Vagifem)
How does it work?
Estradiol works by replacing estrogen that the body makes less of during menopause. Restoring these levels reduces symptoms like hot flashes, night sweats and vaginal dryness while supporting bone health and general comfort.
What does it treat?
Estradiol treats the hot flashes, night sweats and vaginal dryness that can happen during perimenopause and menopause. It can also help prevent post-menopause bone loss.
What forms does it come in?
Estradiol comes in pills, skin patches, gels, sprays and vaginal creams or tablets. The form you use depends on your symptoms and the recommendations of your provider.
Please note that Estradiol vaginal cream, gel and spray are not currently available options on the Dr. B platform.
Estradiol vs. Vagifem
Estradiol comes as a patch and treats symptoms that affect the whole body, like hot flashes and night sweats. Vagifem is a low-dose estrogen tablet inserted into the vagina with an applicator. It works only locally, treating vaginal symptoms like dryness and pain during sex.
How much will it cost?
Dr. B offers online consultations for $15—which is less than most copays. If a HRT prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Estradiol 0.05 mg/24 hr Semiweekly (24 patches) start at $20.15.
* Prices shown with drug discount card applied. Price may differ depending on location.
Estradiol 0.05 mg/24 hr Semiweekly (24 patches)*
Common Questions
Estradiol (generic Vagifem) prescription FAQ
What are the benefits of using Estradiol (generic Vagifem)?
- Reduces hot flashes and night sweats
- Relieves dryness and discomfort in the vagina
- Supports bone health and helps prevent post-menopausal bone loss
- May improve sleep
- Helps replace estrogen that the body makes less of during menopause
Who should not use this medication?
- Pregnant people and those who plan to become pregnant
- Those actively breastfeeding
- People with a history of breast cancer or other estrogen-sensitive cancers
- Anyone with a history of blood clots, stroke, or heart attack
- People with unexplained vaginal bleeding
- Those with active or severe liver disease
- Anyone allergic to Estradiol or its ingredients
If you have any of these conditions, discuss them with your provider before starting Estradiol.
How do I use this medication?
Estradiol is taken in different ways, depending on the form. It may be taken as a pill, worn as a skin patch or inserted vaginally. Always use it exactly as directed by your provider, at the same time each day, if possible.
What happens if I miss a dose?
If you miss your scheduled dose of Estradiol, take it as soon as you remember. If it is almost time to take your next scheduled dose, skip the missed dose. Take your next dose at the scheduled time. Do not double the dose to “catch up” for the dose you missed.
What happens if I use too much?
Can I get Estradiol (generic Vagifem) online?
Yes! Dr. B offers hormone therapy (HT) online in our program, Optimize It. Take a streamlined AI consult to get started. A licensed medical provider will review your information and, if appropriate, send an online Estradiol prescription to your pharmacy of choice.
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MILD
Not everyone will experience side effects when taking Estradiol. When they do present, they’re often mild. Mild Estradiol side effects include:
- Nausea or upset stomach
- Breast tenderness
- Headache
- Bloating or fluid retention
- Mild weight changes
- Mood changes
- Skin irritation at the patch site (if using a patch)
If you experience severe side effects like blood clots, stroke, heart attack or other new or worrying symptoms, contact your provider immediately. Also, report to your provider if you find out that your risk for breast or uterine cancer has increased.