Get a Paroxetine (generic Brisdelle) prescription online
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Paroxetine is a low-dose, non-hormonal medication used as part of hormone therapy (HT) to help reduce the hot flashes and night sweats of menopause. It works by balancing serotonin in the brain, which helps control body temperature. It may also improve sleep and general comfort. Paroxetine is taken by mouth once daily.
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How Dr. B treats HRT
Tell us about your condition with a $15 online consultation.
A medical provider will review your information and prescribe treatment, if appropriate.
Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.
About Paroxetine (generic Brisdelle)
How does it work?
Paroxetine helps balance serotonin, a chemical in the brain that controls body temperature. During menopause, this system can become overactive and cause hot flashes. Paroxetine calms these signals, which helps reduce hot flashes and night sweats—without changing hormone levels.
What does it treat?
Paroxetine is used in hormone therapy (HT) to treat hot flashes and night sweats caused by menopause. It helps reduce how often these symptoms happen and how dramatic they feel. It is a non-hormonal option for those who cannot or prefer not to take hormone therapy.
What forms does it come in?
Paroxetine comes as a low-dose capsule or tablet taken by mouth. It is usually taken once a day, often at night, as directed by your provider.
Paroxetine vs. Brisdelle
Paroxetine and Brisdelle contain the same active ingredient, and both treat hot flashes caused by menopause. Brisdelle is the brand-name version made specifically for menopause symptoms. Paroxetine may be a generic or compounded option prescribed for the same purpose.
The brand drug Brisdelle is not currently available on the Dr. B platform.
How much will it cost?
Dr. B offers online consultations for $15—which is less than most copays. If a HRT prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Paroxetine mesylate7.5 mg (90 capsules) start at $198.99.
* Prices shown with drug discount card applied. Price may differ depending on location.
Paroxetine mesylate7.5 mg (90 capsules)*
Common Questions
Paroxetine (generic Brisdelle) prescription FAQ
What are the benefits of taking Paroxetine (generic Brisdelle)?
- Reduces hot flashes and night sweats
- Does not contain hormones
- May improve sleep
- Taken once daily
- Helpful for people who cannot or prefer not to use hormone therapy
Who should not take this medication?
- Pregnant people or those who plan to become pregnant
- Those actively breastfeeding
- People taking MAO inhibitors (or who stopped taking them within the last 14 days)
- Anyone allergic to Paroxetine or its ingredients
- People taking certain medications like Thioridazine or Pimozide
- Those with a history of serotonin syndrome
- Anyone advised by their provider not to take antidepressant medications
If you have any of these conditions, speak with your licensed provider before starting Paroxetine.
How do you take this medication?
Paroxetine is taken by mouth once a day, with or without food, usually at the same time each day. Always follow your licensed provider’s instructions and do not stop taking it suddenly.
What happens if I miss a dose?
What happens if I take too much?
Can I get Paroxetine (generic Brisdelle) online?
Yes! Dr. B offers hormone therapy (HT) online in our program, Optimize It. To get started, take a streamlined AI consult. A licensed medical provider will review your information. If appropriate, they’ll send a Paroxetine prescription to your chosen pharmacy for pickup.
MILD:

Not everyone experiences side effects when taking Paroxetine. When they do present, they’re often mild. Mild Paroxetine side effects include:
- Nausea or upset stomach
- Sleepiness or feeling tired
- Headache
- Dizziness
- Dry mouth
- Mild trouble sleeping
- Sweating
If you experience severe side effects like serotonin syndrome (agitation or confusion, a high fever, a rapid heart rate, tremors, muscle rigidity etc.), severe mood or behavior changes, a severe allergic reaction or other new or worrying symptoms, contact your provider or pharmacist immediately.