Get a Zoryve prescription online

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Zoryve is a non-steroidal psoriasis treatment. Available as a one-daily topical cream, this phosphodiesterase-4 (PDE-4) inhibitor helps clear up psoriasis patches and reduces inflammation.

* Prescription treatment requires a virtual medical consultation with a medical provider to determine if a prescription is appropriate.

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How Dr. B treats psoriasis

1
Health assessment

Tell us about your condition with a $15 online consultation.

2
Provider review

A medical provider will review your information and prescribe treatment, if appropriate.

3
Get your medication

Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.

About Zoryve

How does it work?

Zoryve is a steroid-free PDE4 inhibitor medication. It works by increasing cyclic adenosine monophosphate (AMP) levels, which play a role in increasing the inflammation that triggers psoriasis, relieving symptoms like dryness, rashes, and plaques.

What does it treat?

Zoryve treats the scaly, itchy patches of psoriasis. It improves these symptoms by restricting the activity of the PDE-4 protein, which causes skin inflammation.

What forms does it come in?

This psoriasis treatment is available as a topical cream that you apply to the affected area of skin, usually once daily.

Zoryve vs. Calcipotriene

Zoryve blocks a specific protein that causes skin inflammation, calming and clearing psoriasis patches. Calcipotriene works differently to slow the growth of skin cells and relieve symptoms like itching, scaling, and redness. Both are safe and effective psoriasis treatments.

Side Effects

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Not everyone experiences side effects when prescribed this medication. When they do occur, they’re often mild. Possible side effects include:

  • Diarrhea
  • Nausea
  • Headache
  • Trouble sleeping

If you experience severe side effects like a serious allergic reaction or seizure—or other new and worrying symptoms—contact your health provider or pharmacist immediately.

More Psoriasis Prescription Treatments

Looking for a different medication? Here are some options.

Common Questions

Zoryve prescription FAQ

What are the benefits of using Zoryve?
  • Reduces inflammation
  • Encourages healing
  • Eases itching
Who should not use this medication?
  • Those allergic to it or its ingredients
  • Those who have moderate or severe liver disease
  • Those who are pregnant or breastfeeding
  • Those who are taking certain other medications, including Theophylline or Ketoconazole

If you have any of these conditions, speak with a licensed provider before using this psoriasis treatment.

How do I use this medication?

In most cases, you apply the cream to the affected areas of your skin once a day. Carefully follow your provider’s instructions for optimal results.

What happens if I miss a dose?

If you miss a dose of Zoryve, take it when you remember. If it’s almost time for the next dose, skip the missed dose and return to your regular schedule. Do not double your dose.

What happens if I use too much?

Taking more of this medication than directed can cause serious side effects such as nausea, vomiting, diarrhea and dizziness.

If you’ve taken too much, call your healthcare provider or local poison control center (800-222-1222) right away.

Can I get Zoryve online?

Yes! Qualifying patients can get a prescription for Zoryve online by taking a convenient Dr. B $15 consultation. A licensed medical provider will review your symptoms and health history. If you qualify for treatment, they'll send your online Zoryve prescription to your pharmacy of choice.

Medically reviewed

To help you stay safe

“I love direct contact with patients—it’s why I chose dermatology! With ample time together, I can use my eyes and mind to diagnose their condition, like a sleuth!”

Dr. Alison Gruen
Dr. Alison Gruen, M.D.Dermatology Advisor

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